Diseases Treated with Cord Blood

Stem Cell Disorders

• Aplastic Anemia (Severe)

• Fanconi Anemia

• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Acute Leukemias

• Acute Lymphoblastic Leukemia (ALL)

• Acute Myelogenous Leukemia (AML)

• Acute Biphenotypic Leukemia

• Acute Undifferentiated Leukemia

Chronic Leukemias

• Chronic Myelogenous Leukemia (CML)

• Chronic Lymphocytic Leukemia (CLL)

• Juvenile Chronic Myelogenous Leukemia (JCML)

• Juvenile Myelomonocytic Leukemia (JMML)

Myeloproliferative Disorders

• Acute Myelofibrosis

• Agnogenic Myeloid Metaplasia (myelofibrosis)

• Polycythemia Vera

• Essential Thrombocythemia

Myelodysplastic Syndromes

• Refractory Anemia (RA)

• Refractory Anemia with Ringed Sideroblasts (RARS)

• Refractory Anemia with Excess Blasts (RAEB)

• Refractory Anemia with Excess Blasts in Transformation (RAEB-T)

• Chronic Myelomonocytic Leukemia (CMML)

Lymphoproliferative Disorders

• Non-Hodgkin’s Lymphoma

• Hodgkin’s Disease

• Prolymphocytic Leukemia

Inherited Erythrocyte Abnormalities

• Beta Thalassemia Major

• Pure Red Cell Aplasia

• Sickle Cell Disease

Liposomal Storage Diseases

• Mucopolysaccharidoses (MPS)

• Hurler Syndrome (MPS-IH)

• Scheie Syndrome (MPS-IS)

• Hunter’s Syndrome (MPS-II)

• Sanfilippo Syndrome (MPS-III)

• Morquio Syndrome (MPS-IV)

• Maroteaux-Lamy Syndrome (MPS-VI)

• Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)

• Adrenoleukodystrophy

• Mucolipidosis II (I-cell Disease)

• Krabbe Disease

• Gaucher’s Disease

• Niemann-Pick Disease

• Wolman Disease

• Metachromatic Leukodystrophy

Histiocytic Disorders

• Familial Erythrophagocytic Lymphohistiocytosis

• Histiocytosis-X

• Hemophagocytosis

Phagocyte Disorders

• Chediak-Higashi Syndrome

• Chronic Granulomatous Disease

• Neutrophil Actin Deficiency

• Reticular Dysgenesis

Congenital Immune System Disorders

• Ataxia-Telangiectasia

• Kostmann Syndrome

• Leukocyte Adhesion Deficiency

• DiGeorge Syndrome

• Bare Lymphocyte Syndrome

• Omenn’s Syndrome

• Severe Combined Immunodeficiency (SCID)

• SCID with Adenosine Deaminase Deficiency

• Absence of T & B Cells SCID

• Absence of T Cells, Normal B Cell SCID

• Common Variable Immunodeficiency

• Wiskott-Aldrich Syndrome

• X-Linked Lymphoproliferative Disorder

Inherited Platelet Abnormalities

• Amegakaryocytosis / Congenital Thrombocytopenia

Plasma Cell Disorders

• Multiple Myeloma

• Plasma Cell Leukemia

• Waldenstrom’s Macroglobulinemia

Other Inherited Disorders

• Lesch-Nyhan Syndrome

• Cartilage-Hair Hypoplasia

• Glanzmann Thrombasthenia

• Osteopetrosis

Other Malignancies

• Breast Cancer

• Ewing Sarcoma

• Neuroblastoma

• Renal Cell Carcinoma